malignant pleural mesothelioma

Mesothelioma is the most common primary tumor of the pleura. There are two main types;
1], localized mesothelioma (benign and malignant types)
2] the diffuse malignant mesothelioma
Causes
There is a strong correlation between exposure to asbestos and developing mesothelioma, although a history of exposure not always obtained in patients who have mesothelioma. There are 2 types of asbestos fibers on the basis of the crystal structure, a serpentine-chrysolite () and b-amphiboles. Included in amphiboles are amosite, tremolte, crocidolite, and anthophyllite. The most damaging is the crocidolite, or better known as blue asbestos.
Located Bening Mesothelioma
These feature are derived from the inner layer of the pleura
The symptoms and signs;
-chest pain
-shortness of breath
-most often asymptomatic, no symptoms (), these tumors are usually discovered on routine chest radiograph
(hypoglycemia-low blood sugar blood is associated with times)
Treatment
Surgery is the main stay of treatment, the tumor is removed by the surgeon and the recurrence of breathing
Treatment
Surgery is the treatment of choice, although the prognosis is very poor
Diffuse malignant mesothelioma
This type of mesothelioma can arise form any part of the pleura and often extend into the peritoneum and in the ribs and chest wall (peritoneal mesothelioma and mesothelioma effusion). It also commonly spreads to the liver, brain and adrenal glands. Histologically malignant mesothelioma have both fibrous mesothelioma sarcomatous () And (papillary epithelial) components.
Research
-CT of the thorax is useful in diagnosing the tumor extension.
Biopsy needle (the surgeon inserts a needle into the pleura to sample the tumor, which is taken to the laboratory to see under the microscope) of the pleura is a necessity.
"The pleural fluid is sucked and taken to the laboratory for microscopic analysis.
Staging of malignant pleural mesothelioma
Stage 1: Involvement the pleura and lungs ipsilateral (affecting only one lung to the left or right lung)
-Stage 2-Involvement of the chest wall, mediastinum (structure in the middle of the heart), pericardial or contralateral side () pleura
Stage 3-blood-distance spread to other organs such as brain, adrenal glands
Treatment
The treatment is discouraging inefficient and rarely survive more than 2 years with an average of 10-14 months. In selected cases with stage 1 pleuropneumonectomy radical surgery can be effective, but long-term survival is rare. Primary radiation therapy can also be used. Combination chemotherapy protocols using a single agent or in combination have also been used, but the result remains disappointing.
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Information on Malignant Pleural Mesothelioma – Bakersfield






